News & Events

28 May 2018

MACH Projects Update - June 2018

The MACH has been busy over the last few months. The following is a snapshot of what we've been working on.

1. Prof David Henry's Data Project

With financial support from MACH, researchers at the Melbourne School of Population and Global Health have commenced an ambitious project to use large linked routinely collected data-bases to assess the safety of medicines in common use in the Australian community. Some of this work will be done in collaboration with Australia's regulator of medicines, the Therapeutic Goods Administration. Ximena Camacho and David Henry at MSPGH had extensive experience of this type of analysis when they worked at the Institute for Clinical Evaluative Sciences in Toronto, Canada, which is Canada's premier health data centre. The intention is to use sophisticated approaches, such as propensity-matched cohorts, nested case-control studies and self-controlled designs and apply these remotely to linked data-sets in Ontario (population 13.5 m) and in Australia (Victoria and New South Wales - population 14.1 m). The latter will be done in collaboration with the Centre for Big Data Research in Health at the University of New South Wales. Both Ontario and the two Australian States have publicly funded healthcare programs that cover prescription medicines. Using careful matching and adjustment procedures the team will attempt to generate un-confounded estimates of the risks of serious harm with medicines used in a variety of different disease states. By combining the statistical power generated by the combined Canadian and Australian populations they will be able to quantify uncommon but serious adverse events.


2. Prof Doug Boyle's Data Project

To address the national initiatives in building capacity in data driven healthcare improvement, the MACH has provided Associate Professor Douglas Boyle with funding to undertake three elements of work:

  • Understanding current data linkage activities utilising primary care data

  • Building deep understandings and trust in routinely-collected GP data

  • Develop an implementation plan for integration of primary care nationwide


3. Indigenous Health Network

The MACH is conducting preliminary capacity mapping in advance of the creation of an Indigenous Health Network, to be made up of the top researchers on Indigenous Health across its 18 partners. The network’s priority focus areas will be in alignment with national priorities set by the Australian Health Research Alliance and the Federal Government and will prepare for future funding opportunities. An Indigenous Health Research Day is in the preliminary planning stages, to be held in the Spring months. Check back with us for more information coming soon.


4. HSIS National Initiative

To address the AHRA national systems level initiative 1 – Health Systems Improvement and Sustainability Framework, MACH research leads will be identifying top health services research priorities and strengths across MACH partners. This will enable and promote future research and change. Keep an eye out for more information to come.


5. Women and Newborn Health Network

The Women and Newborn Health Network at MACH had their first meeting on 27 April, bringing together leading researchers and clinicians in women and newborn health. The network is focussing on upcoming MRFF endometriosis funding and putting together a portfolio of research in preparation for future funding bids.

For more information, please contact MACH Project Officer Jodie Wall:

Further networks are being developed

by the MACH and will take shape in the

coming months. For more information

on our work, networks, or any

of these stories, please contact: or (03) 8344 9973


MACH is an NHMRC recognised Advanced Health Research and Translation Centre.

The mission of MACH is to improve health and wellbeing by integrating medical research, education and clinical care.


187 Grattan Street

Carlton, VIC 3053


+61 (0)3 9035 4960


MACH acknowledges the Traditional Owners of the land on which it works, the Wurundjeri People of the Kulin Nation, and pay respects to its elders past, present and emerging.

All content copyright © 2020 the Melbourne Academic Centre for Health