2018 MACH MRFF
Rapid Applied Research Translation Grants
2018 Rapid Applied Research Translation Projects
The MACH presented funding opportunities for researchers across its partnership through the Medical Research Future Fund (MRFF) Rapid Applied Research Translation (RART) grants scheme. It ultimately funded four research projects, which were completed at the end of 2018.
These projects were aligned with the Medical Research and Innovation Priorities 2016-2018 and the Medical Research and Innovation Strategy 2016-2021 and demonstrated clear evidence of translational outcomes to with an aim of improving health outcomes and driving health system reform.
*This funding is distinct from other MRFF funding streams and is only available via the MACH to its partners.
2018 Rapid Applied Research Translation Grant Scheme
The aim of this funding scheme was to:
improve patient experience by improving care pathways and service connections;
reduce unwarranted variation in healthcare and patient outcomes;
improve the health of certain at-risk groups in Australia, such as Indigenous Australians; and
support innovative clinical trials.
The MACH offered these funding opportunities to MACH partner-affiliated researchers to support translational research projects that would produce tangible outcomes of value to the health system within the short period of 12 months.
Prof Jo Douglass
MACH Partners: Austin Health, Melbourne Health, Northern Health, University of Melbourne, Walter and Eliza Hall Institute, Western Health
Project title: Melbourne Thunderstorm
Epidemic of Asthma:
Solving the puzzle
In 2016, Melbourne suffered an asthma epidemic resulting the activation of disaster codes, overwhelmed emergency services and the deaths of 10 people. To be better prepared for the reoccurrence of such an epidemic, this project determines and monitors those at risk, tracks how air quality impacts them, and extends our ability to provide pollen warnings across additional states in Australia. This study will enable Government and health professionals to provide evidence-based, targeted advice to people with grass pollen allergy on the risks of thunderstorm asthma and to invest in evidence-based treatment and warning systems to avert a repeat of this disaster.
Prof Mingguang He
MACH Partners: Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, St Vincent's Hospital Melbourne, University of Melbourne
Project title: Artificial intelligence-assisted opportunistic screening of diabetic retinopathy at endocrinology clinics
Vision impairment and blindness are major public health problems in Australia with over 50% of the blindness in those aged over 40 years being caused by just three diseases. This project uses artificial intelligence to examine retinal photographs to screen patients for these such diseases before symptoms are noticeable. Given the economic impact of vision impairment and blindness, the successful deployment of these new techniques will significantly improve many patient’s health outcomes.
Prof Andrea Maier
MACH Partners: Melbourne Health, Northern Health, University of Melbourne, Western Health
Project title: Enhancing Muscle POWER in Geriatric Rehabilitation: EMPOWER-GR
The worldwide population is ageing and it is expected that the proportion of people aged 60 years and above will triple over the next 30 years. Sarcopenia – low muscle mass – is a significant problem for us as we age and is often undiagnosed, leading to serious falls, morbidity and even death. The project gathers evidence on the prevalence of sarcopenia across multiple health services in addition to establishing a biobank of blood and muscle/skin samples. This will help researchers better understand loss of muscle mass to address sarcopenia through interventions and educational programs for healthcare professionals.
Prof Ingrid Scheffer AO
MACH Partners: Austin Health, Florey Institute of Neuroscience and Mental Health, Royal Children's Hospital, The University of Melbourne, Walter and Eliza Hall Institute
Project title: Developing precision medicine for the developmental and epileptic encephalopathies
This project explores which genes are involved in epileptic encephalopathies – severe epilepsies that begin in infancy and childhood with devastating outcomes – and, of those, which ones might provide opportunities for new therapies. Stem cells derived from the patient group will be utilised to safely test new pharmaceutical treatments. This project will have significant impact for epilepsy patients and families, enabling a specific diagnosis for affected individuals in whom a genetic mutation is identified.