2019 RART Projects and Fellowships 

(Stage 1)

​The aim of this funding scheme is to:

  • improve patient experience by improving care pathways and service connections;

  • reduce unwarranted variation in healthcare and patient outcomes;

  • improve the health of certain at-risk groups in Australia, such as Indigenous Australians; and

  • support innovative clinical trials.


The MACH offered these two funding opportunities to MACH partner-affiliated researchers (in the form of project grants and research fellowships) to support translational research projects that will produce tangible outcomes of value to the health system within a short period.

This scheme provided distinct opportunities for:

  • researchers wishing to scale up post proof-of-concept translational research projects across multiple MACH partner hospitals in areas of priority

  • early career clinician researchers wishing to protect research time to undertake research with a focus on data and health services research, clinical informatics or conducting innovative clinical trials

Explore our projects

Dr Andrew Bivard

MACH Partners: Austin Health, Florey Institute of Neuroscience and Mental Health, Melbourne Health, St Vincent’s Hospital Melbourne, University of Melbourne, Western Health

Project titleTenecteplase versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (TASTEa) 

Ischemic stroke is a major health burden globally and in Australia. Treatment for ischemic stroke is time critical and is significantly more effective if administered within the first 90 minutes of symptom onset.This clinical trial will identify if early administration of oral thrombolytic agent, tenecteplase prior to hospital can improve outcomes from stroke, and reduce costs compared to standard care of IV alteplase in hospital.

Video coming soon!

A/Prof Luke Burchill

MACH Partners: Austin Health, Melbourne Health, Peter MacCallum Cancer Centre, University of Melbourne

Project titleClosing the gap on Indigenous cardiovascular (CV) health: Improving community outcomes through high impact policy relevant research

CV disease is the largest contributor to the health gap between Indigenous and non-Indigenous Australians. This project will link clinical data collected by Australian general practices, hospitals, and government agencies to determine how variation in CV risk, events and treatment influences Indigenous and non-Indigenous health outcomes. 

A/Prof Adam Deane

MACH Partners: Austin Health, Melbourne Health, Northern Health, Peter MacCallum Cancer Centre, St Vincent’s Hospital Melbourne, Royal Women’s Hospital, University of Melbourne, Western Health

Project titleLiberal glUcose Control in critically Ill patient with pre-existing type 2 Diabetes (LUCID): a phase IIB multi-centre parallel group randomised clinical trial  

Each year more than 30,000 patients with type 2 diabetes require Intensive Care Unit (ICU) admission. Patient outcomes are poor if blood glucose levels are too high, and so patients are treated with insulin infused directly into the bloodstream. This multicentre randomised clinical trial focuses on improving the management of hyperglycaemia in patients with type II diabetes in critical care, so that interventions occur only a higher blood glucose level. This trial aims to reduce hypoglycaemia and other complications of diabetes and ICU stay in this population.

Prof Gustavo Duque

MACH Partners: Austin Health, University of Melbourne, Western Health

Project titleIntegrating Osteoporosis in Primary Care: The Osteoporosis Risk and Management (ORMA) Project 

By 2022, it is estimated that 6.2 million Australians older than 50 years of age will have osteoporosis or osteopenia, a rise of 31% from 2012.  The ORMA Project will simplify the process for GPs to efficiently and earlier identify patients who may be at risk of osteoporotic fractures. In addition, the program will facilitate efficient management of individuals already diagnosed with the disease. 

Prof Harriet Hiscock

MACH Partners: Murdoch Childrens Research Institute, Northern Health, Royal Children's Hospital, University of Melbourne

Project titleImproving the care of children with frequent asthma admissions through partnerships with hospitals, GPs and families

Asthma is the most common chronic childhood illness and accounts for most paediatric hospital admissions. To prevent frequent, costly admissions, we need to understand factors in a child’s care journey associated with re-admissions. This project will follow a group of children who were admitted to one of three hospitals for asthma treatment in 2017 comparing a group of children with at least 1 subsequent asthma re-admission in 2018 to the group of children who are not re-admitted during this time.

A/Prof Craig Nelson

MACH Partners: University of Melbourne, Western Health (including primary care affiliates)

Project titleFuture Health Today Project-Co-design of Prototype 

Future Health Today is a novel e-technology platform to extract primary care performance data for clinical audit and decision support to facilitate chronic disease prevention, management and quality improvement.  The goal of Future Health Today (FHT) is to create a new standard-of-care for patients at risk, or diagnosed with chronic diseases, focused on chronic kidney disease (CKD), type 2 diabetes (T2DM) and cardiovascular disease (CVD).


Future Health Today Project-Co-design of Prototype

Improving the care of children with frequent asthma admissions through partnerships with hospitals, GPs, and families


Integrating Osteoporosis in Primary Care: The Osteoporosis Risk and Management (ORMA) Project 

Artificial intelligence-assisted opportunistic screening of diabetic retinopathy at endocrinology clinics (linked to a previously MACH  funded RART project grant)

Development and validation of a biomarker-guided risk index for the prediction of clinical outcomes in young people at ultra-high risk for psychosis (not linked to a 2019 MACH funded RART project grant)

Learn more about Dr Berger's work


MACH is an NHMRC recognised Advanced Health Research and Translation Centre.

The mission of MACH is to improve health and wellbeing by integrating medical research, education and clinical care.


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