2019 MACH MRFF

Rapid Applied Research Translation 

Successful Grants & Fellowships

Prof David Castle 

MACH Partners: Austin Health, University of Melbourne, St Vincent's Hospital Melbourne

Project titleEvaluating the impact of a psychological intervention to reduce the severe stress and psychological morbidity of people with chronic kidney disease: The Kidney Optimal Health Program (KOHP): Stage 2

Summary: The progressive loss of kidney function leading to end-stage chronic kidney disease (CKD) is a severe and debilitating health problem, with the prevalence of CKD in Australians steadily increasing. Aside from the physical effects, CKD patients experience high rates of comorbid depression and anxiety. The program aims to offer an effective psychosocial intervention that addresses the mental and functional health of CKD patients.

About Prof Castle's Research Project

What is the problem you're trying to solve? 

The progressive loss of kidney function leading to end-stage chronic kidney disease (CKD) is a severe and debilitating health problem, with the prevalence of CKD in Australians steadily increasing. Aside from the physical effects, CKD patients experience high rates of comorbid depression and anxiety.

About this research translation project 

Depression and anxiety are associated with poorer quality of life and functional capacity in CKD, including higher rates of mortality, hospitalisation, dialysis withdrawal and double the rate of kidney transplant rejection. Presently, there is a treatment gap in the prevention or management of these psychosocial problems in CKD. The Kidney Optimal Health Program (KOHP) is an 8-session program that provides a framework for improving both the psychosocial and mental health of individuals. It has been proven to result in significant reductions in mental health symptoms in patients with mental health disorders and can be delivered to patients in both rural and metropolitan areas. Preliminary analysis indicates that individuals who participated in the original program displayed clinically meaningful decreases in levels of depression and anxiety and used comparatively fewer health services. The KOHP will expand by developing strategies to engage primary care providers in the program and mapping cognitive function in participants to assess the impact of program engagement.

What will be the impact? 

The program aims to offer an effective psychosocial intervention that addresses the mental and functional health of CKD patients.

Download this project summary:

For more information on this project, please contact the MACH office:

(03) 8344 9973

mach-admin@unimelb.edu.au

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